Graduate Student, Doug Miller & the Khoshbouei lab publish in May 7, 2018 GliaMiller DR, Shaerzadeh F, Phan L, Sharif N, Gamble-George J, McLaughlin JP, Streit WJ, Khoshbouei H: HIV-1 Tat regulation of dopamine transmission and microglial reactivity is brain region specific. Glia 2018.
Graduate Student, Kevin Strang and colleagues publish in Feb 16, 2018 The Journal of Biological Chemistry.Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI: Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies. J Biol Chem 2018, 293:2408-2421
Graduate Student, Kelly DeMars and the Candelario-Jalil lab publish in Feb 20, 2018 Frontiers in Neuroscience.DeMars KM, McCrea AO, Siwarski DM, Sanz BD, Yang C, Candelario-Jalil E: Protective Effects of L-902,688, a Prostanoid EP4 Receptor Agonist, against Acute Blood-Brain Barrier Damage in Experimental Ischemic Stroke. Front Neurosci 2018, 12:89.
Graduate Student, Latoya Allen receives 2018 Madelyn Lockhart Emerging Scholar Honorable Mention Award.
Latoya Allen is the recipient of the Madelyn Lockhart Emerging Scholar Honorable Mention Award sponsored by the Association for Academic Women (AAW). Latoya is a fifth year graduate student in the laboratory of Dr. Gordon Mitchell. This award recognizes Latoya’s high level of scientific productivity, her contributions to breaking down barriers to success for the students that she mentors, and her outreach activities. The AAW will present her the award at the Women’s History Month Celebration that will be held at the University House on Wednesday, March 14, 2018 at 5:30pm.
The AAW at the University of Florida established the Madelyn Lockhart Dissertation Fellowship in 1996 to honor an outstanding graduate student. One fellowship is awarded to assist in the dissertation phase of the doctoral degree. The award was established to recognize Dr. Madelyn Lockhart who served as Dean of the Graduate School and Dean of International Studies and Programs from 1985 to 1993, Associate Dean from 1981 to 1985 and Assistant Dean from 1973 to 1977 and 1979 to 1981.
Graduate Student, Kelly DeMars & the Candelario-Jalil lab publish in Feb 12, 2018 Biochem Biophys Res CommunDeMars KM, Yang C, Castro-Rivera CI, Candelario-Jalil E: Selective degradation of BET proteins with dBET1, a proteolysis-targeting chimera, potently reduces pro-inflammatory responses in lipopolysaccharide-activated microglia. Biochem Biophys Res Commun 2018, 497:410-415.
Former Grad Student, Dr. Danielle Sambo, Graduate Student, Joe Lebowitz and the Khoshbouei lab publish in Jan 2018 Pharmacology & TherapeuticsSambo DO, Lebowitz JJ, Khoshbouei H: The Sigma-1 Receptor as a Regulator of Dopamine Neurotransmission: A Potential Therapeutic Target for Methamphetamine Addiction. Pharmacol Ther 2018.
Former Grad Student, Dr. Danielle Sambo, Grad Student, Joe Lebowitz and the Khoshbouei lab publish in the Dec 20, 2017 Nature Communications.Sambo DO, Lin M, Owens A, Lebowitz JJ, Richardson B, Jagnarine DA, Shetty M, Rodriquez M, Alonge T, Ali M, Katz J, Yan L, Febo M, Henry LK, Bruijnzeel AW, Daws L, Khoshbouei H: The sigma-1 receptor modulates methamphetamine dysregulation of dopamine neurotransmission. Nat Commun 2017, 8:2228.
Former Grad Student, Dr. Lara Ianov and the Foster Lab publish in the Dec 2017 Frontiers in Aging Neuroscience
Ianov L, De Both M, Chawla MK, Rani A, Kennedy AJ, Piras I, Day JJ, Siniard A, Kumar A, Sweatt JD, Barnes CA, Huentelman MJ, Foster TC: Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment. Front Aging Neurosci 2017, 9:383.
Graduate Student, Kevin Strang and CTRND labs publish in Dec 2017 Journal of Biological Chemistry.Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI: Distinct differences in prion-like seeding and aggregation between tau protein variants provide mechanistic insights into tauopathies. J Biol Chem 2017.
Graduate Student, Emily Koller and the Golde & Chakrabarty labs publish in Nov 28, 2017 Neurobiology of Disease
Strickland MR, Koller EJ, Deng DZ, Ceballos-Diaz C, Golde TE, Chakrabarty P: Ifngr1 and Stat1 mediated canonical Ifn-gamma signaling drives nigrostriatal degeneration. Neurobiol Dis 2017, 110:133-141.
Postdoc, Dr. Caitlin Orsini, Grad Student, Caesar Hernandez & colleagues publish in Oct 27, 2017 Journal of Neuroscience
Orsini CA, Hernandez CM, Singhal S, Kelly KB, Frazier CJ, Bizon JL, Setlow B. Optogenetic inhibition reveals distinct roles for basolateral amygdala activity at discrete timepoints during risky decision making. J Neurosci. 2017 Oct 27;. [Epub ahead of print] PMID: 29079687
Rani A, O’Shea A, Ianov L, Cohen RA, Woods AJ, Foster TC. miRNA in Circulating Microvesicles as Biomarkers for Age-Related Cognitive Decline. Front Aging Neurosci. 2017;9:323. PMID: 29046635 [PubMed]
Hernandez AR, Hernandez CM, Campos KT, Truckenbrod LM, Sakarya Y, McQuail Ph D JA, Carter CS, Bizon JL, Maurer AP, Burke SN. The Anti-Epileptic Ketogenic Diet Alters Hippocampal Transporter Levels and Reduces Adiposity in Aged Rats. J Gerontol A Biol Sci Med Sci. 2017 Oct 12;. [Epub ahead of print] PMID: 29040389
Rutherford NJ, Dhillon JS, Riffe CJ, Howard JK, Brooks M, Giasson BI: Comparison of the in vivo induction and transmission of alpha-synuclein pathology by mutant alpha-synuclein fibril seeds in transgenic mice. Hum Mol Genet 2017.
Rutherford NJ, Brooks M, Riffe CJ, Gorion KM, Howard JK, Dhillon JS, Giasson BI: Prion-like transmission of alpha-synuclein pathology in the context of an NFL null background. Neurosci Lett 2017, 661:114-120.
Hernandez CM, Vetere LM, Orsini CA, McQuail JA, Maurer AP, Burke SN, et al. Decline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344 x brown Norway hybrid rats. Neurobiol Aging. 2017;60:141-152.
McGuiness JA, Scheinert RB, Asokan A, Stadler VC, Lee CS, Rani A, Kumar A, Foster TC, Ormerod BK. Indomethacin Increases Neurogenesis across Age Groups and Improves Delayed Probe Trial Difference Scores in Middle-Aged Rats. Front Aging Neurosci. 2017;9:280. PMID: 28928652 [PubMed]
Dhillon JS, Riffe C, Moore BD, Ran Y, Chakrabarty P, Golde TE, et al. A novel panel of alpha-synuclein antibodies reveal distinctive staining profiles in synucleinopathies. PLoS One. 2017;12(9):e0184731.
Ianov L, Riva A, Kumar A, Foster TC. DNA Methylation of Synaptic Genes in the Prefrontal Cortex Is Associated with Aging and Age-Related Cognitive Impairment. Front Aging Neurosci. 2017;9:249.
Graduate Student, Kevin Strang, Dr. Ben Giasson & colleagues publish in July 31, 2017 Acta Neuropathol CommunStrang KH, Goodwin MS, Riffe C, Moore BD, Chakrabarty P, Levites Y, Golde TE, Giasson BI. Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau. Acta Neuropathol Commun. 2017 Jul 31;5(1):58. PMID: 28760159 [PubMed – in process]
Graduate Student, Kelly DeMars & the Candelario-Jalil lab publish in July 25, 2017 Frontiers in NeurologyDeMars KM, Pacheco SC, Yang C, Siwarski DM, Candelario-Jalil E: Selective Inhibition of Janus Kinase 3 Has No Impact on Infarct Size or Neurobehavioral Outcomes in Permanent Ischemic Stroke in Mice. Front Neurol 2017, 8:363.
Former Graduate Student, Dr. Jenna LeClerc & the Dore Lab publish in June 2017 Frontiers in NeurologyGarcia JM, Stillings SA, Leclerc JL, Phillips H, Edwards NJ, Robicsek SA, Hoh BL, Blackburn S, Dore S: Role of Interleukin-10 in Acute Brain Injuries. Front Neurol 2017, 8:244.
Graduate Student, Hunter Futch & the Golde lab publish in June 2017 Molecular NeurodegenerationFutch HS, Croft CL, Truong VQ, Krause EG, Golde TE: Targeting psychologic stress signaling pathways in Alzheimer’s disease. Mol Neurodegener 2017, 12:49.
Dr. Changjun Yang, Postdoctoral Fellow and colleagues publish in 2017 Aging and DiseaseChangjun Yang, Kelly M. DeMars, Eduardo Candelario-Jalil. Age-Dependent Decrease in Adropin is Associated with Reduced Levels of Endothelial Nitric Oxide Synthase and Increased Oxidative Stress in the Rat Brain.
Former Graduate Student, Dr. Nicole Rutherford & labs publish in May 2017 Molecular NeurodegenerationSorrentino ZA, Brooks MMT, Hudson V, 3rd, Rutherford NJ, Golde TE, Giasson BI, Chakrabarty P: Intrastriatal injection of alpha-synuclein can lead to widespread synucleinopathy independent of neuroanatomic connectivity. Mol Neurodegener 2017, 12:40.
Former Grad Student, Dr. Kim Hawkins & Candelario-Jalil lab publish in April 2017 Brain and BehaviorHawkins KE, DeMars KM, Alexander JC, de Leon LG, Pacheco SC, Graves C, Yang C, McCrea AO, Frankowski JC, Garrett TJ, Febo M, Candelario-Jalil E: Targeting resolution of neuroinflammation after ischemic stroke with a lipoxin A4 analog: Protective mechanisms and long-term effects on neurological recovery. Brain Behav 2017, 7:e00688.